1 (a) Fig. 1.1 is a diagram of the female reproductive system. A B C D E Fig. 1.1 (i) State the letter from Fig. 1.1 that shows the part where: fertilisation occurs … gametes are produced. … [2] (ii) Identify the part labelled B in Fig. 1.1. … [1] (b) Fig. 1.2 shows a student’s description of fertilisation in humans. The description of fertilisation in humans is incorrect. Circle the two incorrect words in the description in Fig. 1.2. Fertilisation is the separation of the nuclei from a sperm cell and an ovary cell. Fig. 1.2 [2] (c) Fig. 1.3 shows how the thickness of the uterus lining changes during the menstrual cycle. 0 2 4 6 8 10 12 14 day of menstrual cycle 16 18 20 22 24 26 28 relative thickness of uterus lining Fig. 1.3 Table 1.1 represents the days during an average menstrual cycle. Table 1.1 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Use Fig. 1.3 and your own knowledge to: (i) place ticks (3) in Table 1.1 to show the days when the uterus lining is shed [1] (ii) place crosses (✗) in Table 1.1 to show the days when the uterus lining is at its thickest. [1] (d) Complete the sentence to define the term reproduction. Reproduction is the processes that make … of the same … of organism. [2] [Total: 9]

1(a)(i) A ; E ; 2 1(a)(ii) uterus ; 1 1(b) separation ; ovary; 2 1(c)(i)  under days 1–4 ; 1 1(c)(ii) X under days 24–26 ; 1 1(d) more ; kind ; 2

1 (a) Fig. 1.1 is a diagram of the female reproductive system. A B C D E Fig. 1.1 (i) State the letter from Fig. 1.1 that shows the part where: fertilisation occurs … gametes are produced. … [2] (ii) Identify the part labelled B in Fig. 1.1. … [1] (b) Fig. 1.2 shows a student’s description of fertilisation in humans. The description of fertilisation in humans is incorrect. Circle the two incorrect words in the description in Fig. 1.2. Fertilisation is the separation of the nuclei from a sperm cell and an ovary cell. Fig. 1.2 [2] (c) Fig. 1.3 shows how the thickness of the uterus lining changes during the menstrual cycle. 0 2 4 6 8 10 12 14 day of menstrual cycle 16 18 20 22 24 26 28 relative thickness of uterus lining Fig. 1.3 Table 1.1 represents the days during an average menstrual cycle. Table 1.1 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 Use Fig. 1.3 and your own knowledge to: (i) place ticks (3) in Table 1.1 to show the days when the uterus lining is shed [1] (ii) place crosses (✗) in Table 1.1 to show the days when the uterus lining is at its thickest. [1] (d) Complete the sentence to define the term reproduction. Reproduction is the processes that make … of the same … of organism. [2] [Total: 9]

1(a)(i) A ; E ; 2 1(a)(ii) uterus ; 1 1(b) separation ; ovary; 2 1(c)(i)  under days 1–4 ; 1 1(c)(ii) X under days 24–26 ; 1 1(d) more ; kind ; 2

4 (a) Human immunodeficiency virus (HIV) is a sexually transmitted infection. The number of new HIV infections in one country was monitored. The results are shown in Fig. 4.1. 0 1000 1999 2000 2001 2002 2003 2004 year 2005 2006 2007 2008 2009 2000 3000 4000 number of new HIV infections 5000 6000 7000 8000 Fig. 4.1 The number of new infections has decreased since 2002. (i) Calculate the difference in number of new HIV infections between 2002 and 2009. … [1] (ii) Suggest two reasons why the number of new HIV infections has decreased since 2002. 1 … … 2 … … [2] (iii) Place a tick (3) in the box to show one way HIV can be transmitted. holding hands sharing cooking utensils through breast milk genetically inherited [1] (b) HIV infects white blood cells. Fig. 4.2 shows a photomicrograph of some blood. A white blood cell can be seen in the centre. X Fig. 4.2 (i) Name the part of the white blood cell labelled X in Fig. 4.2. … [1] (ii) Name the other type of cells visible in Fig. 4.2. … [1] (iii) State two functions of white blood cells. 1 … 2 … [2] (iv) Name the part of the blood that transports hormones. … [1] [Total: 9]

4(a)(i) 7000 – 3100 = 3900 ; 1 4(a)(ii) any two from: use of condoms / femidoms ; screening blood transfusions ; education ; use of clean needles / needle exchange programmes ; regular HIV testing ; preventative medication ; AVP ; e.g. practise of abstinence 2 4(a)(iii) through breast milk ticked ; 1 4(b)(i) nucleus ; 1 4(b)(ii) red blood cell ; 1 4(b)(iii) phagocytosis ; antibody production ; 2 4(b)(iv) plasma ; 1

4 (a) Fig. 4.1 is a diagram of the male reproductive system in humans. A B C D E F Fig. 4.1 Identify the letter from Fig. 4.1 that represents the: part where sperm is produced, … part which secretes the fluid that sperm swim in, … tube which carries both semen and urine. … [3] (b) State the name of the part of the female reproductive system that releases gametes. … [1] (c) The statements in Table 4.1 describe either asexual or sexual reproduction. Complete Table 4.1 to identify the type of reproduction each statement describes. Table 4.1 statement type of reproduction offspring are genetically identical to each other produces zygotes involves the fusion of nuclei [2] (d) Fig. 4.2 is a diagram representing the reproduction of a type of organism called a hydra. Fig. 4.2 Identify if this organism is reproducing asexually or sexually. Use evidence from Fig. 4.2 to give a reason for your answer. type of reproduction … reason … … [1] (e) Reproduction and respiration are characteristics of living things. State two other characteristics of living things. 1 … 2 … [2] [Total: 9]

4(a) E ; C ; A ; 3 4(b) ovary ; 1 4(c) asexual sexual sexual ;; 2 4(d) asexual offspring produced by only one parent ; 1 4(e) any two from: movement ; sensitivity ; growth ; excretion ; nutrition ; 2

Cambridge IGCSE Co-ordinated Sciences · 0654

IGCSE Co-ordinated Sciences (0654) Reproduction past paper questions

Revise IGCSE Co-ordinated Sciences (0654) — Reproduction with real Cambridge past-paper questions grouped by topic, each shown with its marking scheme. Working one topic at a time targets exactly the skill each question tests.

115 free questions from 2016–2021, each with its marking scheme. Open the full topical bank to filter by subtopic, paper, and year.

Reproduction in IGCSE Co-ordinated Sciences 0654 exams, 2020–2025

Across 2020–2025, Reproduction accounted for 152 questions worth 781 marks in Cambridge IGCSE Co-ordinated Sciences (0654) papers.

By year
Year	Questions	Marks
2020	20	121
2021	25	119
2022	27	121
2023	28	150
2024	23	120
2025	29	150

Most-tested subtopics

B15.3 Sexual reproduction in plants394 marks
B15.4 Sexual reproduction in humans305 marks
B15.2 Sexual reproduction165 marks

Appears in

Paper 1 · 42 qs
Paper 2 · 40 qs
Paper 3 · 27 qs
Paper 4 · 30 qs
Paper 5 · 6 qs
Paper 6 · 7 qs

All most-tested Co-ordinated Sciences topics

2021 May/Jun · Paper 3 · Q1 · 9 marks
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2021 May/Jun · Paper 3 · Q1 · 9 marks
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2021 Feb/Mar · Paper 3 · Q4 · 9 marks
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2021 Oct/Nov · Paper 3 · Q4 · 9 marks
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2021 Feb/Mar · Paper 1 · Q10 · 1 mark
Marking scheme
Mark scheme — 2021 Paper 1 Q10
Answer: A
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