1 (a) Fig. 1.1 is a diagram of the parts of the eye. A B C D Fig. 1.1 (i) The boxes on the left show the letters of the parts of the eye in Fig. 1.1. The boxes on the right show some functions of parts of the eye. Draw lines to link the letter of the part from Fig. 1.1 to its function. B C D A letter in Fig. 1.1 carries impulses to the brain contains light receptors focusses light onto the retina refracts light as it enters the eye function [3] (ii) Draw an X on Fig. 1.1 to show the position of the blind spot. [1] (b) Fig. 1.2 shows the change that occurs in the eye after it is exposed to bright light. before exposure after exposure Fig. 1.2 Describe the change to the eye in Fig. 1.2 and explain why this change is important. … … … … … … … [3] (c) The eye is a sense organ. The skin is another type of sense organ. State two stimuli that skin responds to. 1 … 2 … [2] [Total: 9]

1(a)(i) A carries impulses to brain B contains light receptors C focusses light onto the retina D refracts light as it enters the eye ;;; 3 3 marks for 4 correct lines 2 marks for 2 or 3 correct lines 1 mark for 1 correct line R each additional line 1(a)(ii) X drawn on the blind spot ; 1 1(b) any three from: iris widens / AW ; pupil becomes smaller / AW ; to reduce the amount of light entering (the eye) / to prevent too much light entering the eye / to adapt to bright light conditions / AW ; to prevent damage (to the retina) ; ref. to (pupil light) reflex ; 3 1(c) any two from: temperature ; touch / pressure ; pain ; 2

3 (a) Fig. 3.1 shows the number of deaths in one country that were due to excessive alcohol consumption. 4000 2009 2010 2011 year 2012 2013 4400 4800 5200 5600 4200 4600 5000 number of deaths due to excessive alcohol consumption 5400 Fig. 3.1 Describe the results shown in Fig. 3.1. Use the data to support your answer. … … … … … … … [3] (b) Describe two short-term effects of excessive alcohol consumption on the nervous system. 1 … … 2 … … [2] (c) State the name of one organ damaged by long-term excessive alcohol consumption. … [1] (d) Alcohol dehydrogenase is an enzyme that breaks down alcohol in the body. Fig. 3.2 shows the activity of alcohol dehydrogenase at different pH values. 3 enzyme activity 5 7 pH 9 11 4 6 8 10 Fig. 3.2 (i) State the pH value with the highest enzyme activity in Fig. 3.2. … [1] (ii) State the pH value with the lowest enzyme activity in Fig. 3.2. … [1] (iii) Suggest one other factor that could affect the activity of the enzyme alcohol dehydrogenase. … [1] (e) Enzymes are biological catalysts. Define the term catalyst. … … … [2] (f) Enzymes are proteins. Circle the elements that all enzymes contain. calcium carbon hydrogen iodine iron magnesium nitrogen oxygen [2] [Total: 13]

2(c) any three from: asexual reproduction: sexual reproduction: 1 both produce offspring / AW 2 one parent two parents 3 genetically identical offspring / clone genetically different offspring 4 no involvement of gametes (named) gametes 5 no fertilisation fertilisation / fusion of gametes 6 no variation variation 7 fast slow 8 mitosis meiosis (and mitosis) 9 less energy required more energy required ;;; 3 one mark per row response does not have to be in a table (a) To earn marks, you must describe the trend shown in the graph, noting whether the number of deaths increased or decreased, and support your description with specific data values from the figure. (b) To earn marks, you need to describe two distinct short-term effects of excessive alcohol consumption on the nervous system.

4 (a) Fig. 4.1 is a diagram of a plant cell. … … … … Fig. 4.1 Identify the parts of the plant cell in Fig. 4.1 by labelling them in the spaces provided, using words from the list. cell membrane cell wall chloroplast cytoplasm nucleus vacuole [4] (b) The boxes on the left show parts of a plant cell. The boxes on the right show the functions of the parts. Draw lines to link each part with its function. Draw four lines. part function contains the genetic material cell wall filled with sap and supports the plant cell chloroplast made of cellulose and strengthens the plant cell nucleus site of photosynthesis vacuole site of respiration [4] (c) Xylem is a specialised plant tissue. State two functions of xylem tissue. 1 … 2 … [2] (d) Plant shoots and roots respond to stimuli. Fig. 4.2 is a photograph of a plant that has been grown in the dark. The plant has been grown with the pot in this position and is showing a tropic response to this stimulus. Fig. 4.2 (i) State the name of the tropic response shown in Fig. 4.2. … [1] (ii) Describe how the roots would respond to the same stimulus. … … … [1] [Total: 12]

3(a) arrow drawn from chuckwallas to coyotes ; 1 3(b) producer consumer herbivore carnivore coyote   jack rabbit   rattlesnake   yucca plant  ;;;; 4 one mark for each correct column R each additional tick 3(c) mountain lion ; 1 3(d) (population of) chuckwallas would decrease ; idea of there would be, less food / less energy / more competition (for food) ; 2 4(a) plant cell labelled from top to bottom: cell wall ; cytoplasm ; chloroplast ; cell membrane ; 4 4(b) part funtion ;;;; contains the genetic material cell wall filled with sap and supports the plant cell chloroplast made of cellulose and strengthens the plant cell nucleus site of photosynthesis vacuole site of respiration 4 one mark per part A line between chloroplast and contains the genetic material R other additional lines 4(c) conduction / transport / transfer of, water / mineral ions ; support ; 2 4(d)(i) gravitropism ; 1 4(d)(ii) roots would grow downwards / AW ; 1

4 (a) The box on the left contains the words ‘Aerobic respiration’. The boxes on the right show some sentence endings. Draw lines to make three correct sentences about aerobic respiration. Aerobic respiration involves the action of enzymes. occurs in animals only. produces water. requires carbon dioxide. releases less energy than anaerobic respiration. requires oxygen. [3] (b) One effect of the release of the hormone adrenaline is to increase blood glucose concentration. This allows more aerobic respiration to occur. (i) Place ticks (✓) in the correct boxes to show other effects of the release of adrenaline on the body. change in the genotype decreased breathing rate development of lung cancer increased pulse rate widened pupils [2] (ii) State the name of the gland that releases adrenaline. … [1] (iii) State how adrenaline is transported to its target organs. … … [1] (c) State the names of two hormones involved in the development of secondary sexual characteristics in humans. 1 … 2 … [2] (d) State the name of the organ that secretes the hormone insulin. … [1] (e) Organs, tissues and specialised cells are structures in the body that perform a particular function. Write these parts of the body in order of size from smallest to largest. cell DNA molecule organ organ system tissue smallest … … … … largest … [2] [Total: 12]

2(c) any three from: asexual reproduction: sexual reproduction: 1 both produce offspring / AW 2 one parent two parents 3 genetically identical offspring / clone genetically different offspring 4 no involvement of gametes (named) gametes 5 no fertilisation fertilisation / fusion of gametes 6 no variation variation 7 fast slow 8 mitosis meiosis (and mitosis) 9 less energy required more energy required ;;; 3 one mark per row response does not have to be in a table (a) To earn marks, you must draw three correct lines linking 'Aerobic respiration' to its correct sentence endings, such as 'involves the action of enzymes', 'produces water', and 'requires oxygen'. (b)(i) To earn marks, you must place ticks in the boxes next to 'increased pulse rate' and 'widened pupils'. (b)(ii) You earn the mark by stating 'adrenal gland'. (b)(iii) You earn the mark by stating that adrenaline is transported in the 'blood' or 'bloodstream'. (c) To earn marks, you must state the names of two hormones involved in the development of secondary sexual characteristics, such as 'testosterone' and 'oestrogen' (or 'estrogen').

23 The list shows some processes that take place in a human body. 1 production of new red blood cells 2 transmission of nerve impulses from the eyes to the brain 3 diffusion of gases into and out of the lungs Which processes use energy released by respiration? A 1 and 2 only B 1 and 3 only C 2 and 3 only D 1, 2 and 3

Answer: A To earn the mark, a student must correctly identify that the production of new red blood cells and the transmission of nerve impulses from the eyes to the brain are processes that use energy released by respiration.

Cambridge IGCSE Biology · 0610

IGCSE Biology (0610) Coordination and response past paper questions

These questions cover the nervous system, reflexes, hormones, and homeostasis.

305 free questions from 2017–2021, each with its marking scheme. Open the full topical bank to filter by subtopic, paper, and year.

Coordination and response in IGCSE Biology 0610 exams, 2020–2025

Across 2020–2025, Coordination and response accounted for 348 questions worth 1,204 marks in Cambridge IGCSE Biology (0610) papers.

By year
Year	Questions	Marks
2020	61	190
2021	64	223
2022	58	195
2023	51	197
2024	51	182
2025	63	217

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Paper 1 · 128 qs
Paper 2 · 139 qs
Paper 3 · 41 qs
Paper 4 · 37 qs
Paper 5 · 2 qs
Paper 6 · 1 q

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2021 Oct/Nov · Paper 3 · Q1 · 9 marks
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2021 May/Jun · Paper 3 · Q3 · 13 marks
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2021 Feb/Mar · Paper 3 · Q4 · 12 marks
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2021 May/Jun · Paper 3 · Q4 · 12 marks
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2021 May/Jun · Paper 1 · Q23 · 1 mark
Marking scheme
Mark scheme — 2021 Paper 1 Q23
Answer: A
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